Hazardous Drug Diversion of Valproate from a General Practitioner to his Patient’s Dog
نویسندگان
چکیده
General practitioners are key stakeholders in good prescribing practices. More than half of patients have at least one unintended medication discrepancy upon hospital admission, some of which have the potential to cause severe discomfort or clinical deterioration. We report a case of a drug mistakenly administered to a 66-year-old man with cirrhosis and chronic alcoholism. Based on his regular prescription, he received 1 g/day of valproate during a hospitalization for cardiac valve surgery. This anticonvulsant was initially prescribed by his general practitioner for his epileptic dog and has been added to his own prescription to be covered by the French national health insurance. The aim of this article is to emphasize that general practitioners, physicians, and pharmacists have a major role to play in preventing the diversion of prescription drugs and limiting the risk of adverse drug events.
منابع مشابه
Seizure in Patients with Antiepileptic Drug Overdose: Study on Patients Admitted To Shoushtari Hospital in Shiraz
Background: Poisoning with non-barbiturate anti-epileptics (carbamazepine, sodium valproate and phenytoin) shows a growing trend. The objective of this study was to investigate clinical manifestations of poisoned patients with these medications. Methods: This prospective study was conducted in the Shiraz Shoushtari Hospital during a two-year period from 2010 to 2012. Poisoning was confirmed acc...
متن کاملSome Serum Biochemical Alterations after Urinary Diversion with Colonic Segment in Dog
Objective- To evaluate the some serum biochemical alterations after urinary diversion with colonic segment.Design- Experimental in vivo study.Animals- five adult healthy mixed breed dogs of both sexes weighing between 25-40 kg. Procedures- In this approach, fifteen centimeters of the descending colon with preservation of its mesenteric vessels was resected and this segment longitudinally was op...
متن کاملEffects of Sodium Valproate on the Replication of Herpes Simplex Virus Type 1: An in Vitro Study
Background: Sodium valproate, an anticonvulsant drug, is reported to stimulate Human Immunodeficiency Virus type 1 and Human cytomegalovirus replication. Since epileptic patients undergoing sodium valproate therapy may suffer from various virus infections, the effect of this drug on replication of viruses especially those affecting neuronal tissues such as Herpes simplex virus type 1 is worthy ...
متن کاملA Case Report for Ischemic Heart Disease Treatment in a 53-Year-Old Man Based on Iranian Integrative Medicine in Bojnurd
Background: Coronary artery disease is one of the most common causes of death in the world. Despite significant advances in the diagnosis and treatment of these diseases, they are still considered a major health problem in the world. The purpose of this report is to provide the clinical experience of Iranian Integrative Medicine, which has the greatest therapeutic effect in the...
متن کاملThe Therapeutic Effects of Low-Frequency Electrical Stimulations Adjunct to Sodium Valproate on Seizure and Behaviors
Introduction: Consuming antidepressant medications induce several problems leading to the need for alternative agents for emotional disturbances. Antidepressant medications increase the seizure risk; thus, alternative treatments, like Antiepileptic Drugs (AED), might be useful for patients with epilepsy comorbid with a psychiatric disorder. The present study evaluated the behavioral effects of ...
متن کامل